What does disease progression mean?
Simply put, disease progression in Ankylosing Spondylitis means the disease could worsen over time. Ankylosing Spondylitis causes inflammation, which damages the spinal bones. The damaged bones are replaced with repair tissue, on which tiny new bones are formed. These newly formed abnormal bones use up the space in between themselves, ultimately resulting in fusion or ‘bamboo spine’![3]
Ankylosing Spondylitis is a silently progressing disease. Fusion of the spine is the most feared outcome of Ankylosing Spondylitis.4
What does this imply?
Spinal damage and fusion can be potentially disabling.[3] Fusion of the spinal bones may translate into:[3]
- Inability to move freely
- Loss of function
- Disability
- Pain
- Fatigue
Since Ankylosing Spondylitis affects people in their 20’s or 30’s, neglect or improper treatment can result in a lifetime of immobility.[3]
AS/FTF/IN2011102420/10/11/2020
In Collabration with Novartis